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Talipexole dihydrochloride
CAS No. 36085-73-1
Talipexole dihydrochloride ( B-HT 920 dihydrochloride; Domnin )
产品货号. M26624 CAS No. 36085-73-1
Talipexole dihydrochloride is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥259 | 有现货 |
|
| 5MG | ￥413 | 有现货 |
|
| 10MG | ￥664 | 有现货 |
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| 25MG | ￥1264 | 有现货 |
|
| 50MG | ￥2252 | 有现货 |
|
| 100MG | ￥3621 | 有现货 |
|
| 200MG | ￥5233 | 有现货 |
|
| 500MG | ￥8084 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Talipexole dihydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Talipexole dihydrochloride is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.
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产品描述Talipexole dihydrochloride is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.(In Vivo):Intracisternal injection of 10 μg/kg Talipexole dihydrochloride promotes vagal-mediated reflex bradycardia induced by injection of angiotensin in β-adrenoceptor-blocked dogs. Intravenous administration of Talipexole dihydrochloride at 30 mcg/kg initially caused an increase in blood pressure in cats. Then there is the long-term drop in blood pressure and heart rate.
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同义词B-HT 920 dihydrochloride; Domnin
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体PARP1; PARP2
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研究领域——
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适应症——
化学信息
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CAS Number36085-73-1
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分子量282.2
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分子式C10H17Cl2N3S
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纯度>98% (HPLC)
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溶解度——
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SMILESCl.Cl.Nc1nc2CCN(CC=C)CCc2s1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.P. de Souza, et al. 574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours. ABSTRACT ONLY
VOLUME 31, SUPPLEMENT 4, S490, SEPTEMBER 01, 2020.
VOLUME 31, SUPPLEMENT 4, S490, SEPTEMBER 01, 2020.
产品手册
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